Music
From Music to Science: A Student's Unique Journey in Biochemistry Research
2025-04-21

A student at the University of Missouri has carved out a unique path, blending his passion for music with scientific discovery. Will Thives Santos, initially pursuing a career in music, found an unexpected calling in biochemistry during a gap year caused by the pandemic. Now a senior majoring in biochemistry with a minor in jazz studies, Santos has accumulated nearly four years of research experience in a plant lab on campus. Recently, he co-authored a research paper with his mentor, Craig Schenck, exploring how certain chemicals affect plant growth. This study not only advances agricultural science but also highlights the value of interdisciplinary thinking.

Growing up in Brazil, Santos initially envisioned a future as a professional musician. However, circumstances led him to explore the world of science. During his freshman year, he joined the Freshmen Research in Plants (FRIPS) program, sparking a newfound interest in scientific research. Partnering with Craig Schenck, an assistant professor in biochemistry, Santos dove into studying toxic compounds produced by plants as defense mechanisms. His creativity and problem-solving skills quickly set him apart, making him an invaluable member of the team.

Schenck noted that Santos approaches research with the same discipline and creativity he applies to playing the guitar. Despite the challenges inherent in scientific exploration, Santos remains undeterred by setbacks. He views failure as an essential part of discovery, much like a musician refining their craft through practice. This mindset has fostered innovation in the lab and strengthened Santos' confidence in contributing to the field.

Their collaborative efforts culminated in a groundbreaking study published in Plant Journal. The research delves into the mechanism of azetidine-2-carboxylic acid, a compound that disrupts plant root growth by interfering with protein folding. By understanding this process, scientists can potentially develop sustainable solutions for managing invasive plants in agriculture. Santos' contributions to this project exemplify the synergy between scientific rigor and creative thinking.

Beyond the lab, Santos continues to nurture his love for music, playing guitar with the university’s Concert Jazz Band and an alternative rock band called The Park. As he embarks on a doctoral journey in biological engineering, Santos reflects on the parallels between music and science. Both fields require dedication, creativity, and a desire to contribute to something greater than oneself. Looking ahead, Santos envisions his work serving as a foundation for future discoveries, inspiring others to build upon his contributions and further expand human knowledge.

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